: any of several microbial growth factors
especially : a fatty acid C8H14O2S2 that is essential for the oxidation of alpha-keto acids (such as pyruvic acid) in metabolism

Examples of lipoic acid in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Omega-3 fatty acids plus alpha-lipoic acid. Megan Nunn, Verywell Health, 29 Apr. 2026 The milk thistle extract and alpha lipoic acid could make the supplement more effective. Bestreviews, Chicago Tribune, 29 Jan. 2026 Peptides and alpha-lipoic acid are among the ingredients that help lift and tighten the delicate skin on your neck, while niacinamide and vitamin C work to brighten dark spots. Ava Darrin, ELLE, 16 Nov. 2022 This included an omega-3 fatty acid called alpha lipoic acid (ALA), which offers anti-inflammatory effects. Lauren O'Connor, Health, 31 Dec. 2025 See All Example Sentences for lipoic acid

Word History

Etymology

lip-, lipo-

First Known Use

circa 1951, in the meaning defined above

Time Traveler
The first known use of lipoic acid was circa 1951

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Cite this Entry

“Lipoic acid.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/lipoic%20acid. Accessed 7 Jul. 2026.

Medical Definition

: any of several microbial growth factors
especially : a crystalline compound C8H14O2S2 that is essential for the oxidation of alpha-keto acids (as pyruvic acid) in metabolism

called also protogen

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